skip to main content
US FlagAn official website of the United States government
dot gov icon
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
https lock icon
Secure .gov websites use HTTPS
A lock ( lock ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Explore Research Products in the PAR
It may take a few hours for recently added research products to appear in PAR search results.


  • Home
  • Search Results
  • Page 1 of 5

Search for: All records

Creators/Authors contains: "Wuest, William M"

Note: When clicking on a Digital Object Identifier (DOI) number, you will be taken to an external site maintained by the publisher. Some full text articles may not yet be available without a charge during the embargo (administrative interval).
What is a DOI Number?

Some links on this page may take you to non-federal websites. Their policies may differ from this site.

  1. ; ; ; ; ; ; ; ; ; ; et al (, ACM)
    Free, publicly-accessible full text available August 3, 2026
  2. ; (, Tetrahedron)
    Full Text Available 
  3. ; (, Tetrahedron Letters)
    Full Text Available 
  4. ; ; ; ; ; ; ; ; (, ChemMedChem)
    Full Text Available 
  5. ; (, Bioorganic & Medicinal Chemistry)
    null (Ed.)
    Full Text Available 
  6. ; ; (, ACS Infectious Diseases)
    null (Ed.)
    Full Text Available 
  7. ; ; ; ; ; ; ; ; (, ACS Infectious Diseases)
    Full Text Available 
  8. ; (, RSC Medicinal Chemistry)
    The World Health Organization considers the discovery of new treatments for P. aeruginosa a top priority. Virulence attenuating combination therapy (VACT) is a pragmatic strategy to improve bacterial clearance, repurpose outmoded antibiotics, improve drug efficacy at lower doses, and reduce the evolution of resistance. In vitro and in vivo studies have shown that adding a quorum sensing inhibitor or an extracellular polymeric substance repressor to classical antibiotics synergistically improves antipseudomonal activity. This review highlights why VACT could specifically benefit cystic fibrosis patients harboring chronic P. aeruginosa infections, outlines the current landscape of synergistic combinations between virulence-targeting small-molecules and anti-pseudomonal drugs, and suggests future directions for VACT research. 
    more » « less
    Full Text Available 
  9. ; ; (, ACS Omega)
  10. ; ; ; ; ; ; (, Bioorganic & Medicinal Chemistry Letters)
    null (Ed.)
    Full Text Available